Wnt/[beta]-catenin signaling regulates vertebrate limb regeneration

Article Abstract:

The gain- and loss-of-function experiments of specific members of the Wnt/[beta]-catenin pathway during appendage regeneration have shown that this pathway is not only necessary for regeneration, but is also able to promote limb/fin regeneration in axolotl, Xenopus, and zebrafish. The molecular and cellular processes involved during limb embryogenesis and limb regeneration have suggested a mechanism, whereby variations in the concentration and/or spatiotemporal distribution of developmental regulators might allow regeneration to occur.

Genetic aspects, Genetic research, Zebra fish, Zebra fishes

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Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs

Article Abstract:

Cytostatic factor (CSF)-mediated arrest of metaphase in vertebrate eggs is discussed. CSF does not refer to a molecule, rather to an activity found in the egg that does not become fertilized. Progress in understanding b iochemistry and cell biology of C SF arrest mostly comes from study of Xenopus oocytes.

Biochemistry, Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Cellular Biology, Usage, Cell division, Cytology, Meiosis, Ovum

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TFIID - specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo

Article Abstract:

The article presents general cessation of transcription caused by mutations in the yeast TFIID-specific protein TAF40. It discusses the possibility of identifying mutants that disrupt function without causing protein degradation.

Analysis, Gene mutations, Gene mutation, Proteins, Yeast, Yeast (Food product)

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